冠脉通片联合氯吡格雷治疗冠心病心绞痛的临床研究

目的 探讨冠脉通片联合硫酸氢氯吡格雷片治疗冠心病心绞痛的临床疗效.方法 选取2019年5月—2020年5月在天津市南开区中医医院治疗的冠心病心绞痛患者94例,根据就诊顺序分为对照组(47例)和治疗组(47例).对照组口服硫酸氢氯吡格雷片,75 mg/次,1次/d;治疗组在对照组的基础上口服冠脉通片,1.8 g/次,3次...

Clinical study on Guangmaitong Tablets combined with clopidogrel in treatment of angina pectoris of coronary heart disease

Objective To investigate the effect of Lanqin Oral Liquid combined with Amoxicillin and Clavulanate Potassium Dispersible Tablets in treatment of acute tonsillitis in children and its effect on the serum levels of interleukin-2 (IL-2), interleukin-6 (IL-6) and soluble interleukin-2 receptor (SIL-2R) in children. Methods A total of 192 children with acute tonsillitis admitted to Maternal and Child Health Hospital of Shijingshan District from January 2017 to July 2018 were selected as the research objects and randomly divided into control group 1 (n=63), control group 2 (n=64) and observation group (n=65). Children in control group 1 were given Amoxicillin and Clavulanate Potassium Dispersible Tablets, 1 tablet/time for 3-7 years old children, 1.5 tablets/time for children aged 8-12 years, children older than 12 years old took 2 tablets/time, and the use frequency was three times daily. Children in control group 2 were given Lanqin Oral Liquid, 1 branch/time for 3-8 years old children, 1.5 branch/time for 8-12 years old children, children order than 12 years old took 2 branch/time, the use frequency was three times daily, and treatment duration was 7 days. The treatment regimen of the children in the observation group was Lanqin Oral Liquid combined with Amoxicillin and Clavulanate Potassium Dispersible Tablets, which was the same as that of the control group. One course of treatment lasted for 7 days. After treatment, the clinical efficacy, antifebrile duration, symptom improvement time, and recurrence rate of patients in the three groups were observed, and the levels of IL-2, IL-6 and SIL-2R in the three groups were compared before and after treatment. Results After treatment, the total effective rate of clinical treatment in the observation group was 95.38%, significantly higher than 84.13% in control group 1 and 81.25% in control group 2, with statistically significant difference (P<0.05). After treatment, the antifebrile time, symptom improvement time, and recurrence rate of the children in the observation group were significantly lower than those in the control group 1 and 2, with statistically significant differences (P<0.05). There was significant difference in symptom improvement time between control group 1 and control group 2 (P<0.05). After treatment, serum levels of IL-2, IL-6, and sIL-2R were significantly lower in the three groups than before treatment (P<0.05). Moreover, the serum levels of IL-2, IL-6 and sIL-2R in the observation group were significantly lower than those in the control group 1 and 2 after treatment, with statistically significant differences (P<0.05). Conclusion Lanqin oral liquid combined with Lanqin Oral Liquid combined with Amoxicillin and Clavulanate Potassium Dispersible Tablets in treatment of acute tonsillitis can effectively promote the recovery of disease and improve the immune ability of the body, which is worthy of clinical promotion.