艾盐包热熨联合耳穴压豆治疗胃癌术后化疗临床研究

目的:观察艾盐包热熨联合耳穴压豆对胃癌术后化疗所致胃肠道反应及睡眠质量的影响。方法:选取胃癌术后患者90例,按随机数字表法分为观察组和对照组各45例。2组术后均给予奥沙利铂+卡培他滨片化疗方案治疗,对照组在化疗同时给予耳穴压豆治疗,观察组在对照组基础上联合艾盐包热熨穴位治疗,2组均连续治疗6周。比较2组消化道症状积分、匹兹堡睡眠质量指数量表(PSQI)评分及生活质量卡氏评分、临床疗效,并记录2组治疗期间胃肠道不良反应发生率。结果:观察组总有效率为71.1%,高于对照组44.4%(P<0.05)。治疗后,2组口腔、恶心呕吐、腹泻、便秘积分均较治疗前降低(P<0.05),观察组口腔、恶心呕吐、腹泻、便秘积分均低于对照组(P<0.05)。治疗后,2组睡眠时间、入眠时间、睡眠质量、药物催眠、PSQI总积分均较治疗前降低(P<0.05),观察组睡眠时间、入眠时间、睡眠质量、药物催眠、PSQI总积分均显著低于对照组(P<0.05)。观察组食欲降低、腹胀便秘及恶心呕吐的发生率均明显低于对照组(P<0.05)。治疗后,2组生活质量卡氏评分均升高(P<0.05),观察组生活质量卡氏评分高于对照组(P<0.05)。结论:艾盐包热熨联合耳穴压豆能够改善患者胃癌术后化疗胃肠道反应程度和发生率,提高睡眠质量,改善生活质量,疗效确切。

Clinical Study on Hot Medicinal Compress with Moxa-Salt Bag Combined with Auricular Point Pressing with Beans for Chemotherapy After Surgery of Gastric Cancer

Objective:To observe the effect of hot medicinal compress with moxa-salt bag combined with auricular point pressing with beans on sleeping quality, and gastrointestinal reactions induced by chemotherapy after surgery of gastric cancer. Methods:A total of 90 cases of patients after surgery of gastric cancer were selected and divided into the observation group and the control group,45 cases in each group. Both groups were given chemotherapy of oxaliplatin and capecitabine tablets after surgery, and the control group was treated with auricular point pressing with beans at the same time. The observation group was additionally treated with hot medicinal compress with moxa-salt bag at points based on the treatment of the control group. Both groups were continuously treated for six weeks. The scores of digestive tract symptoms,Pittsburgh Sleep Quality Index(PSQI), and Karnofsky Performance Status for measuring quality of life, as well as clinical effect were compared between the two groups. During treatment,the incidence of adverse reactions in gastrointestinal tract was recorded. Results:The total effective rate was 71.1% in the observation group,higher than that of 44.4% in the control group(P<0.05). After treatment, the scores of oral cavity, nausea and vomiting, diarrhea, and constipation in the two groups were decreased when compared with those before treatment(P<0.05),and the scores in the observation group were lower than those in the control group(P<0.05). After treatment,the sleeping duration,the time of falling asleep,sleeping quality,medicine hypnosis,and the total score of PSQI in the two groups were decreased when compared with those before treatment(P<0.05), and the five indexes above in the observation group were significantly lower than those in the control group(P<0.05). The incidence of poor appetite,abdominal distension,constipation,as well as nausea and vomiting in the observation group was significantly lower than that in the control group(P<0.05). After treatment,the scores of Karnofsky Performance Status for measuring quality of life in the two groups were increased(P<0.05),and the score in the observation group was higher than that in the control group(P<0.05). Conclusion:The therapy of hot medicinal compress with moxa-salt bag combined with auricular point pressing with beans can improve the degree and the incidence of gastrointestinal reactions induced by chemotherapy after surgery of gastric cancer. It can improve sleeping quality and life quality,with defined curative effect.