| 中医药干预肠道菌群防治高血压合并认知障碍的探讨 |
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| 作者姓名： | 洪于兴 宁美 颜习武 常诚 |
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| 作者单位： | 南京中医药大学附属医院，江苏 南京 210029 |
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| 基金项目： | 国家自然科学基金(81673759);江苏省中医药局科技项目(BE2017770);第四批全国中医临床优秀人才研修项目(国中医药人教函〔2017〕124号);符为民江苏省名老中医药专家工作室(苏中医科教〔2016〕6号);符为民全国名老中医药专家传承工作室(国中医药人教函〔2018〕134号)。 |
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| 摘 要： | 肠道菌群失调存在于高血压及认知障碍患者中, 肠道菌群影响人体血压水平、大脑功能和宿主行为, 从而与高血压合并认知障碍相关。补益肝肾、平肝潜阳、活血化瘀类中药调整肠道菌群对防治高血压合并认知障碍的治疗具有一定优势。从肠道菌群与高血压以及认知障碍的关系、中医药调节肠道菌群改善高血压合并认知障碍的研究现状等角度进行综述, 旨在探究高血压合并认知障碍防治的新靶点、新思路。
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| 关 键 词： | 中医药 肠道菌群 益生菌 高血压合并认知障碍 |
| 收稿时间： | 2020-05-11 |
Discussion on the Prevention and Treatment of Hypertension with Cognitive Impairment by Intervention of Intestinal Flora with Traditional Chinese Medicine |
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| Authors: | HONG Yu-xing NING Mei YAN Xi-wu CHANG Cheng |
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| Institution: | The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, China |
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| Abstract: | Intestinal flora imbalance existed in patients with hypertension and cognitive impairment.Intestinal flora affected human blood pressure level,brain function,host behavior and might be related to hypertension with cognitive impairment.Regulation of intestinal flora with Chinese herbs such as tonifying liver and kidney,tranquilizing liver and suppressing Yang,promoting blood circulation and removing blood stasis had great advantages in preventing and treating hypertension with cognitive impairment.This paper reviewed the relationship among intestinal flora,hypertension and cognitive impairment,and the research status of TCM regulating intestinal flora in the treatment of hypertension with cognitive impairment,aiming to explore novel targets and ideas for preventing and treating hypertension with cognitive impairment. |
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| Keywords: | traditional Chinese medicine intestinal flora probiotics hypertension with cognitive impairment |
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