ADC平均值及最小值在鉴别良、恶性四肢软组织肿瘤中的价值

目的:探讨ADC平均值及最小值在鉴别四肢软组织肿瘤良恶性中的价值.方法:搜集经病理证实的53例四肢软组织肿瘤患者,其中良性24例,恶性29例,53例患者均行MRI及DWI检查,分别测量病灶的ADC平均值及ADC最小值.采用独立样本t检验比较良、恶性四肢软组织肿瘤的ADC平均值及ADC最小值差异;采用受试者工作特征(RO...

Value of mean ADC and minimum ADC in identifying benign and malignant soft tissue tumors of extremities

Objective:To explore the value of mean ADC and minimum ADC values in identifying benign and malignant soft tissue tumors of extremities.Methods:A total of 53 patients with soft tissue tumors of the extremities confirmed by pathology were collected,24 benign and 29 malignant.53 patients were examined by MRI with DWI.The mean ADC and minimum ADC values of the lesions were measured,and the independent sample t test was used for statistics analysis.The difference between mean ADC and minimum ADC of benign and malignant soft tissue tumors were compared.The receiver operating characteristic(ROC)curve was used to evaluate the differential diagnostic efficacy of the two groups.Results:The mean ADC values of 24 benign and 29 malignant soft tissue tumors were(1.289±0.231)×10^-3 mm/s^2 and(0.960±0.221)×10^-3 mm/s^2 with statistically significant difference(P=0.000).The minimum ADC values of 24 benign and 29 malignant tumors were(1.118±0.233)×10^-3 mm/s^2 and(0.702±0.206)×10^-3 mm/s^2 with statistically significant difference(P=0.000).The results of ROC curve analysis showed that the area under the curve(AUC)of the mean ADC was 0.866 and the AUC of the minimum ADC was 0.910.The differential diagnostic value of the minimum ADC was better than that of the mean ADC.The best diagnostic point of the minimum ADC was 0.968×10^-3 mm/s^2,the diagnostic sensitivity was 83.3%,and the specificity was 89.7%.Conclusion:The minimum ADC is better than the mean ADC in the differential diagnosis of benign and malignant soft tissue tumors of the extremities,which is helpful for the formulation of clinical treatment plans and prognosis evaluation.