Phenotypic and genotypic mupirocin resistance among Staphylococci causing prosthetic joint infection |
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| Authors: | Rotger Margalida Trampuz Andrej Piper Kerryl E Steckelberg James M Patel Robin |
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| Institution: | Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic College of Medicine, 200 First St. SW, Rochester, MN 55905, USA. |
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| Abstract: | Mupirocin MICs and mupA presence were determined in 108 staphylococci causing prosthetic joint infection. Zero of 35 isolates (0%) of methicillin-susceptible Staphylococcus aureus, 4/15 (27%) methicillin-resistant S. aureus isolates, 3/16 (19%) methicillin-susceptible coagulase-negative staphylococci, and 11/42 (26%) methicillin-resistant coagulase-negative staphylococci were mupirocin resistant. mupA was detected in all five high-level mupirocin-resistant staphylococci and one mupirocin-susceptible staphylococcus. |
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