高密度脂蛋白与冠状动脉支架植入术后再狭窄的关系

目的探讨再次入院造影复查时血高密度脂蛋白胆固醇水平与冠状动脉支架植入术后再狭窄的关系。方法根据再次冠状动脉造影复查结果,将370例行冠状动脉内支架术并随访造影结果的患者分为再狭窄组与非再狭窄组,对两组临床情况及生物化学指标进行回顾性分析。结果370例患者中有487支靶血管置入支架,94例患者的123支靶血管发生再狭窄。单因素分析显示再狭窄组的高密度脂蛋白胆固醇水平显著低于非再狭窄组,差异有显著性(P<0.05);二分类多因素Logistic回归分析显示低高密度脂蛋白胆固醇水平(高密度脂蛋白胆固醇≤1.04mmol/L)为冠状动脉内再狭窄的独立危险因素。结论提示血高密度脂蛋白胆固醇水平与冠状动脉支架植入术后再狭窄密切相关。

The Relationship Between High Density Lipoprotein Cholesterol and Intracoronary In-stent Restenosis

Aim To evaluate the relationship between high-density lipoprotein cholesterol and intracoronary in-stent restenosis during angiographic follow-up.Methods 370 patients were successfully underwent coronary stent implantation with a follow-up study of angiography.They were divided into restenosis group and non-restenosis group.In-stent restenosis was defined as luminal diameter narrowing of intracronary stent by 50% or greater.Results In 370 patients,487 coronary stents were implanted.In-stent restenosis occur...