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Pathogenic DPYD Variants and Treatment-Related Mortality in Patients Receiving Fluoropyrimidine Chemotherapy: A Systematic Review and Meta-Analysis |
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| Authors: | Bhavina B. Sharma Karan Rai Heather Blunt Wenyan Zhao Tor D. Tosteson Gabriel A. Brooks |
| Affiliation: | 1. Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA Contributed equally;2. Geisel School of Medicine at Dartmouth, Lebanon, New Hamphsire, USA Contributed equally;3. Biomedical Libraries, Dartmouth College, Hanover, New Hampshire, USA;4. Department of Biomedical Data Science, Geisel School of Medicine, Lebanon, New Hampshire, USA;5. Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA |
| Abstract: | |
| Keywords: | 5-fluorouracil Capecitabine DPYD Dihydropyrimidine dehydrogenase deficiency Pharmacogenomics |