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Inhibition of heat shock protein 90 destabilizes receptor tyrosine kinase ROR1 in lung adenocarcinoma |
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| Authors: | Behnoush Khaledian Ayumu Taguchi Kazuo Shin-ya Lisa Kondo-Ida Noritaka Kagaya Motoshi Suzuki Taisuke Kajino Tomoya Yamaguchi Yukako Shimada Takashi Takahashi |
| Affiliation: | 1. Division of Molecular Carcinogenesis, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya, Japan Division of Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan Division of Advanced Cancer Diagnostics, Department of Cancer Diagnostics and Therapeutics, Nagoya University Graduate School of Medicine, Nagoya, Japan;2. Division of Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan Division of Advanced Cancer Diagnostics, Department of Cancer Diagnostics and Therapeutics, Nagoya University Graduate School of Medicine, Nagoya, Japan;3. National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan;4. Division of Molecular Carcinogenesis, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya, Japan Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Nagoya, Japan;5. Division of Molecular Carcinogenesis, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya, Japan |
| Abstract: | |
| Keywords: | geldanamycin HSP90 lung adenocarcinoma proteasomal degradation ROR1 |