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Histiocytic and Dendritic Cell Sarcomas of Hematopoietic Origin Share Targetable Genomic Alterations Distinct from Follicular Dendritic Cell Sarcoma |
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| Authors: | Lucas R. Massoth Yin P. Hung Judith A. Ferry Robert P. Hasserjian Valentina Nardi G. Petur Nielsen Sam Sadigh Vinayak Venkataraman Martin Selig Alison M. Friedmann Wesley Samore Jonathan Keith Killian Riza Milante Joseph Giessinger Kathleen Foley-Peres Chelsea Marcus Eric Severson Daniel Duncan Smruthy Sivakumar Jeffrey S. Ross Vikram Desphande Shakti H. Ramkissoon Jo-Anne Vergilio Abner Louissaint Lawrence R. Zukerberg Erik A. Williams |
| Affiliation: | 1. Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA Contributed equally as co-first authors.;2. Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA;3. Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA;4. Department of Pediatrics, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA;5. Department of Pediatrics, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA;6. Foundation Medicine, Inc., Cambridge, Massachusetts, USA;7. Department of Dermatology, Jose R. Reyes Memorial Medical Center, Manila, Philippines;8. A.T. Still University School of Osteopathic Medicine, Mesa, Arizona, USA;9. Department of Biology, Bristol Community College, Fall River, Massachusetts, USA;10. Foundation Medicine, Inc., Cambridge, Massachusetts, USA Department of Pathology, State University of New York Upstate Medical University, Syracuse, New York, USA;11. Foundation Medicine, Inc., Cambridge, Massachusetts, USA Wake Forest Comprehensive Cancer Center and Department of Pathology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA;12. Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA Contributed equally as co-senior authors. |
| Abstract: | |
| Keywords: | Malignant histiocytosis Follicular dendritic cell sarcoma Histiocytic sarcoma Interdigitating dendritic cell sarcoma Targeted therapy |