| 新型冠状病毒肺炎临床治疗药物最新研究进展 |
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| 引用本文： | 顾觉奋. 新型冠状病毒肺炎临床治疗药物最新研究进展[J]. 中国新药杂志, 2021, 0(2): 154-161 |
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| 作者姓名： | 顾觉奋 |
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| 作者单位： | 中国药科大学生命与科学学院 |
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| 摘 要： | 新型冠状病毒肺炎(coronavirus disease 2019,COVID-19)正在世界范围内流行.作为冠状病毒,新型冠状病毒(SARS-CoV-2)和严重急性呼吸综合征冠状病毒(SARS-CoV)都通过人血管紧张素转化酶2(ACE2)受体侵入宿主细胞.面对疫情异常严峻的现状,目前尚缺乏疫苗和尚无特异性针对该病毒...
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| 关 键 词： | 新型冠状病毒肺炎 新型冠状病毒 最新临床研究进展 治疗药物 作用机制 |
The latest progress in research on clinical therapeutic agents of COVID-19 |
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| GU Jue-fen. The latest progress in research on clinical therapeutic agents of COVID-19[J]. Chinese Journal of New Drugs, 2021, 0(2): 154-161 |
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| Authors: | GU Jue-fen |
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| Affiliation: | (Instirute of Life Science and Technology,China Pharrmaceutical Universily,Nanjing 210009,China) |
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| Abstract: | COVID-19 has been becoming popular all over the worldwide. As a coronavirus,both SARSCo V-2 and SARS-Co V invade host cells through ACE2 receptor. Facing the extremely severe epidemic situation of COVID-19,there is a lack of vaccine and specific antiviral drug for this virus at present. Clinically,supportive treatment and symptomatic treatment are still the main measures. The roles of COVID-19 and ACE2 in SARS-Co V-2 were briefly introduced in this article. The results of the latest clinical trials of potential anti-COVID-19 drugs and the possible mechanisms of action of related drugs were summarized,in order to fully understand the development process of COVID-19 and direction of drug research thus to provide ideas for further study of COVID-19 drug therapy and vaccine development. |
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| Keywords: | COVID-19 SARS-Co V-2 latest clinical research progress therapeutic drug mechanism of action |
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