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十二指肠胃食管反流所致急性气管炎的病理变化
引用本文:丛保忠,汪琪.十二指肠胃食管反流所致急性气管炎的病理变化[J].中国基层医药,2004,11(10):1197-1198.
作者姓名:丛保忠  汪琪
作者单位:150056,黑龙江,哈尔滨,哈尔滨铁路分局医院
摘    要:目的 了解十二指肠胃食管反流(DGER)所致急性气管炎的病理学变化。方法 将实验组的幼兔复制成DGER动物模型,应用光镜和扫描电镜观察气管组织。结果 气管粘膜层的纤毛及柱状上皮细胞变性、脱落;粘膜下层炎性水肿。结论 DGER反流液中的胃酸和胆汁酸等双重攻击因子可直接导致气管的化学性炎症损伤。

关 键 词:急性气管炎  十二指肠胃食管反流  化学性炎症  炎性  粘膜下层  水肿  胃酸  结论  目的  实验
修稿时间:2004年7月21日

Pathological changes in acute tracheitis induced by duodenogestroesophageal reflux
CONG Bao zhong,WANG Qi.Hospital of Harbin Branch of Railway,Heilongjiang,China.Pathological changes in acute tracheitis induced by duodenogestroesophageal reflux[J].Chinese Journal of Primary Medicine and Pharmacy,2004,11(10):1197-1198.
Authors:CONG Bao zhong  WANG QiHospital of Harbin Branch of Railway  Heilongjiang    China
Institution:CONG Bao zhong,WANG Qi.Hospital of Harbin Branch of Railway,Heilongjiang,150056,China
Abstract:Objective To understand the pathological changes in acute tracheitis induced by duodenogestroesophageal reflux(DGER).Methods The young rabbits of experiment group were used esfablish animal model.We observed the tissue in trachea with microscope and scanning electron microscope.Results Cilia and ciliated columned epithelium were found with degeneration and swelling in the trachea mucosa.The submucosa was found with inflammatory edema.Conclusion The gastric fluid and the bile directly caused trachea damage with chemical inflammation.
Keywords:Duodenogestroesophageal reflux  Acute tracheitis  Pathology  Scanning electron microscope
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