电针结合偏振光对腰椎间盘突出症患者腰腿疼痛及血清MMP-3的影响

目的：观察电针配合偏振光对腰椎间盘突出症患者腰腿疼痛的镇痛效果，以及对血清基质金属蛋白酶-3（MMP-3）含量的影响。方法：将93例腰椎间盘突出症患者，分为电针配合偏振光组（观察组）31例、电针组（对照1组）30例和偏振光组（对照2组）32例。观察组取肾俞、大肠俞、环跳、委中、承山、昆仑穴，行电针治疗，并配合偏振光照射；对照1组行电针治疗，取穴同观察组；对照2组行偏振光照射治疗。观察3组治疗前后疼痛视觉模拟评分（VAS）及血清基质金属蛋白酶（MMP-3）含量变化情况。结果：治疗15d后，3组VAS及血清MMP-3含量均较治疗前明显降低（P<0.05)，且观察组更低于对照1组及对照2组（P<0.05），对照1组与对照2组间比较差异无统计学意义。结论：电针配合偏振光为治疗腰椎间盘突出症较理想的方法，其机制可能与治疗后病变部位血清MMP-3的降低有关。

Effect of electroacupuncture combined with polarized light intervention on serum matrix metalloproteinase-3 in patients with lumbar disc lesions pain

Objective: To observe the clinical effectiveness of electroacupuncture combined with polarized light for lumbar disc lesions and analyze its effect on serum matrix metalloproteinase-3 (MMP-3) in patients with lumbar disc lesions. Method: Ninety-three cases of lumbar disc lesions were randomly divided into three groups: the electroacupuncture combined with polarized light group (n=31) (treatment group), the electroacupuncture group (n=30) (control group 1), and polarized light group (n=32) (control group 2). The treatment group was given electroacupuncture on Shenshu (BL 23), Dachangshu (BL 25), Huantiao (GB 30), Weizhong (BL 40), Chengshan (BL 57), and Kunlun (BL 60) and polarized light, once a day for 15 days. The control groups were treated as the treatment group with the electroacupuncture and polarized light respectively. After treatment the visual analogue scale (VAS) and the MMP-3 contents in serum were observed. Result: After treatment for 15 days, the VAS values and serum MMP-3 levels were significantly decreased in the three groups as compared with those before treatment (P<0.05). The VAS values and serum MMP-3 levels in treatment group were obviously decreased as compared with the control groups (P<0.05), and there was no significant difference between the two control groups. Conclusion: Electroacupuncture combined with polarized light has a good effectivness on lumbar disc lesions pain probably by decreasing the serum MMP-3 levels in the local site.