| 细胞模型在降糖中药研究中的应用 |
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| 引用本文： | 沙雯君,陆灏. 细胞模型在降糖中药研究中的应用[J]. 上海中医药杂志, 2015, 49(5): 111-113 |
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| 作者姓名： | 沙雯君 陆灏 |
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| 作者单位： | 上海中医药大学附属曙光医院内分泌科,上海,201203;上海中医药大学糖尿病研究中心,上海,201203,上海中医药大学附属曙光医院内分泌科,上海,201203;上海中医药大学糖尿病研究中心,上海,201203 |
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| 基金项目： | 上海市中医临床重点实验室资助项目(14DZ2273200)；上海市卫生局中医药事业发展三年行动计划项目(ZYSNXD-CC-YJXYY,ZYSNXD-CC-ZDYJ046) |
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| 摘 要： | 对近年糖尿病胰岛素抵抗细胞模型及胰岛系细胞模型的相关文献进行综述,介绍降糖中药复方含药血清及中药单体在体外研究中取得的进展。糖尿病体外细胞模型以肝、脂肪、骨骼肌三大胰岛素靶组织细胞和胰腺、胰岛素瘤分离细胞为主,功能特点不同的细胞模型可为降糖中药的筛选和降糖机制的进一步研究提供支持。
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| 关 键 词： | 细胞模型 糖尿病 中药 综述 |
| 收稿时间： | 2014-12-10 |
Application of cell models for the research of Chinese medicine with antidiabetic effect |
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| SHA Wen-jun and LU Hao. Application of cell models for the research of Chinese medicine with antidiabetic effect[J]. Shanghai Journal of Traditional Chinese Medicine, 2015, 49(5): 111-113 |
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| Authors: | SHA Wen-jun and LU Hao |
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| Affiliation: | Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine;Diabetes Research Centre, Shanghai University of Traditional Chinese Medicine and Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine;Diabetes Research Centre, Shanghai University of Traditional Chinese Medicine |
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| Abstract: | This paper reviews the related literatures on cell models such as diabetes insulin resistance cell models and islet cell models, and introduces the research progress on drug serum and monomer of Chinese herbs in vitro. The diabetes cell models are mainly target tissue cells and insulinoma isolated cells. Aims to provide references for the further research on screening of Chinese herbs and its hypoglycemic mechanism. |
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| Keywords: | cell model diabetes Chinese medicine review |
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