不同部位淋球菌感染实验室诊断方法的比较

目的 评价三种不同淋球菌检测方法在不同部位淋球菌感染诊断的临床意义。方法 采用培养、涂片和血清抗体三种试验,对429例临床上疑似淋病病人进行诊断。结果 泌尿生殖道急性淋菌感染阳性检出率从高到低依次为染色涂片79.3％,培养法71.5％和抗体试验2.9％;泌尿生殖道慢性淋病感染阳性检出率从高到低依次为抗体试验53.3％、染色涂片8.3％和培养5.0％;口腔及肛门直肠淋球菌感染阳性检出率从高到低依次为培养64.3％、染色涂片50.4％和抗体试验9.6％;表皮淋球菌感染阳性检出率从高到低依次为培养70.4％、染色涂片61.3％和抗体试验4.5％。结论 实验室在淋病诊断时,应根据淋球菌感染部位和病人患病时间选择合适的方法,否则,将影响诊断的准确性。

Sensitivity Comparison of N. Gonorrhoeae Tests to Different Samples from Different Infectious Sites

To evaluate the sensitivity of three kinds of N. Gonorrhoeae (NG) tests, culture and stain as well as antibody test, to different samples from different infectious sites in gonorrhea patients. Methods 429 suspect gonorrhea patients were detected for N. Gonorrhoeae with culture, stain and antibody test. Results The positive rates of NG stain, culture and antibody test to the samples from acute urogenital tracts of gonorrhea patients were 79.3%, 71.5% and 2.9%, respectively, and those from chronic urogenital tracts 8.3%, 5.0% and 53.3%, respectively. The positive rates of NG stain, culture and antibody test to the samples from oropharynx, anus and rectum of gonorrhea patients were 50.4 %, 64.3% and 4.5%, respectively; and those from skin were 61.3%, 70.4% and 4.5%, respectively. Conclusion The factors such things as infectious sites and time of the gonorrhea patients should be taken into account when to choice which test will be performed in order to ensure the quality of NG laboratory diagnosis.