不同孕期孕妇碘营养状况的研究

目的探讨不同孕期孕妇碘营养的差异,评价妊娠不同时期对孕妇碘营养状况的影响,为科学指导孕妇不同时期的碘摄入提供理论依据。方法利用碘催化砷铈反应原理,采用冷消解快速尿碘定量检测方法测定914例孕妇随意尿的尿碘含量。结果914例孕妇尿碘中位数是218μg/L,其中尿碘≤100μg/L的比率为19.26%,尿碘50μg/L的比率为5.58%。而孕早、中、晚期孕妇尿碘中位数分别是138μg/L、147μg/L、298μg/L,其中尿碘150μg/L的比率分别为63.64%,50.99%,26.44%,尿碘≤100μg/L的比率分别为27.27%,25.25%,16.19%,尿碘50μg/L的比率分别为9.09%,6.93%,4.65%,孕早、中期尿碘水平均低于孕晚期(P均0.01),低尿碘率均高于孕晚期(P均0.01)。低尿碘组中孕中、晚期的尿碘水平均低于孕早期(P均0.05),高尿碘组中孕晚期的尿碘水平均高于孕早、中期(P均0.05)。结论孕早、中期孕妇的碘营养水平较孕晚期低,部分个体碘摄入量不足。孕早、中期是评价和纠正孕妇碘营养状况的最佳时机,应根据不同孕期孕妇个体碘的需求,合理指导碘摄入。

Study on status of iodine nutrition of pregnant women in different gestation periods

Objective It is to approach the difference of iodine nutrition of pregnant women in different gestation periods and evaluate the status of iodine nutrition of pregnant women in different gestation periods for providing a theoretical basis for the scientific guidance of iodine intake in different periods.Methods The contents of urine iodine in random urine of 914 cases of pregnant women were measured with rapid urinary iodine using cold digestion method of quantitative detection using iodine catalytic reaction mechanism of Arsenic-Cerium.Results The median of urine iodine in 914 patients was 218 μg/L.Of them,the ratio of urine iodine ≤100 μg/L was 19.26% and that <50 μg/L was 5.58%.The median of urine iodine in early gestation,mid-gestation and late-gestation was 138 μg/L,147 μg/L and 298 μg/L respectively.Of them,the ratio of urine iodine <150 μg/L was 63.64%,50.99% and 26.44% respectively,that ≤100 μg/L was 27.27%,25.25% and 16.19% respectively and that <50 μg/L was 9.09%,6.93% and 4.65% respectively.The urine iodine levels in early gestation and mid-gestation were both lower than that in late gestation(both P<0.01) and the low urine iodine rates in early gestation and mid-gestation were both higher than that in late gestation(both P<0.01).The urine iodine levels in mid-gestation and late gestation in low urine iodine group were both lower than that in early gestation(both P<0.05) and that in late gestation in high urine iodine group was both higher than that in early gestation and mid-gestation(both P<0.05).Conclusion The iodine nutrition level of pregnant women in early gestation and mid-gestation are both lower than that in late gestation and the iodine intake in partial patients is poor.Early gestation and mid-gestation are the best occasion for evaluating and correcting the iodine nutrition status of pregnant women.Pregnant women ought to be direct iodine intake reasonably according to their needs in different periods.