| 急性心肌梗死患者植入国产西罗莫司支架后心率震荡的动态分析 |
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| 引用本文： | 施亚明,孙剑萍,吴春阳,来士洲,宗永忠,王斌,施国富. 急性心肌梗死患者植入国产西罗莫司支架后心率震荡的动态分析[J]. 岭南心血管病杂志, 2011, 17(5): 387-389. DOI: 10.3969/j.issn.1007-9688.2011.05.013 |
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| 作者姓名： | 施亚明 孙剑萍 吴春阳 来士洲 宗永忠 王斌 施国富 |
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| 作者单位： | 盐城市第三人民医院心内科,江苏盐城,224001 |
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| 基金项目： | 江苏省“六大人才高峰”第四批资助项目(项目编号:07-B-004) |
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| 摘 要： | 目的探讨急性心肌梗死患者植入国产西罗莫司洗脱支架后心率震荡的动态变化。方法应用动态心电图技术分别记录76例急性心肌梗死患者（支架组）支架植入后24h内、1周、3个月、6个月、12个月和24个月的心电图信息，计算各时段的震荡起始（TO）和震荡斜率（TS）。并与同期未行再灌注治疗的急性心肌梗死患者53例（对照组）进行对比分析。结果支架组支架植入术后24h的震荡起始（-0．21％±1．95％vs.0．26％±1．71％，P〈0．01）和震荡斜率[（13．73±6．48）ms／RR vs.（1．21±0．53）ms／RR，P〈0．01]与对照组心肌梗死后24h比较，明显改善，差异有统计学意义，并在随后的24个月中保持这种趋势。尽管对照组患者的震荡斜率在3个月后得到改善（P〈0．05），但不如支架组改善明显，差异有统计学意义（P〈0．05）。结论国产西罗莫司洗脱支架能长期改善急性心肌梗死患者的心率震荡，从而减少临床恶性心律失常事件的发生。
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| 关 键 词： | 心肌梗死 血管成形术，经腔，经皮冠状动脉 支架 西罗莫司 心率震荡 |
Mid-and long-term effects of domestic produced sirolimus drug-eluting stent on heart rate turbulence in patients with acute myocardial infarction |
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| SHI Ya-ming,SUN Jian-ping,WU Chun-yang,ZHUShi-zhou,ZONG Yong-zhong,WANG Bing,SHI Guo-fu. Mid-and long-term effects of domestic produced sirolimus drug-eluting stent on heart rate turbulence in patients with acute myocardial infarction[J]. South China Journal of Cardiovascular Diseases, 2011, 17(5): 387-389. DOI: 10.3969/j.issn.1007-9688.2011.05.013 |
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| Authors: | SHI Ya-ming SUN Jian-ping WU Chun-yang ZHUShi-zhou ZONG Yong-zhong WANG Bing SHI Guo-fu |
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| Affiliation: | SHI Ya-ming,SUN Jian-ping,WU Chun-yang,ZHU Shi-zhou,ZONG Yong-zhong,WANG Bing,SHI Guo-fu(Department of Cardiology,The Third People's Hospital of Yancheng,Yancheng Jiangsu 224001,China) |
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| Abstract: | Objectives To investigate the mid-and long-term effects of domestic produced sirolimus drug-eluting stent on heart rate turbulence in patients with acute myocardial infarction.Methods According to the different therapies,patients with acute myocardial infarction were divided into 2 groups: percutaneous coronary intervention(PCI) group(n=76) and routine medical treatment group(n=53).The 24 h ambulatory eletrocardiolography was performed 24 h,1 week,3 months,6 months,12 months,and 24 months after PCI.Turbulen... |
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| Keywords: | myocardial infarction percutaneous coronary intervention stent sirolimus heart rate turbulence |
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