| 辛伐他汀改善慢性肺源性心脏病患者右心室功能的作用研究 |
| |
| 引用本文： | 孟丽琴. 辛伐他汀改善慢性肺源性心脏病患者右心室功能的作用研究[J]. 岭南心血管病杂志, 2011, 17(5): 398-401. DOI: 10.3969/j.issn.1007-9688.2011.05.016 |
| |
| 作者姓名： | 孟丽琴 |
| |
| 作者单位： | 张家港市第一人民院心内科,江苏张家港,215600 |
| |
| 摘 要： | 目的 评价辛伐他汀改善慢性肺源性心脏病(肺心病)患者有心室功能的作用及相关机制.方法 选择2009年2月至2010年4月55例老年慢性阻塞性肺病(COPD)合并慢性肺心病患者,按随机数字表法分为辛伐他汀组(27例)和常规治疗组(28倒).两组均接受常规治疗,辛伐他汀组在常规治疗的基础上加用口服辛伐他汀(20 mg/d)...
|
| 关 键 词： | 肺源性心脏病 辛伐他汀 慢性阻塞性肺疾病 高血压,肺性 一氧化氯 内皮素 |
Effect of simvastatin on right ventricular function in patients with chronic obstructive pulmonary diseases |
| |
| MENG Li-qin. Effect of simvastatin on right ventricular function in patients with chronic obstructive pulmonary diseases[J]. South China Journal of Cardiovascular Diseases, 2011, 17(5): 398-401. DOI: 10.3969/j.issn.1007-9688.2011.05.016 |
| |
| Authors: | MENG Li-qin |
| |
| Affiliation: | MENG Li-qin(Department of Cardiology,The First People's Hospital of Zhangjiagang City,Zhangjiagang,Jiangsu 215600,China) |
| |
| Abstract: | Objectives To evaluate the effects of simvastatin on right ventricular function in patients with chronic obstructive pulmonary disease(COPD) and to explore the protective mechanism.Methods Fifty five patients with COPD were randomly divided into simvastatin group(n=27) and routine group(n=28) from Feb.2009 to Apr 2010.Both two groups were given routine treatment and the simvastatin group were given simvastatin(20 mg/d) supplement in addition.Nitric oxide(NO),endothelin-1(ET-1),brain natriuretic peptide(BNP)... |
| |
| Keywords: | chronic cor pulmonale simvastatin chronic obstructive pulmonary disease pulmonary hypertension nitric oxide endothelin |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
