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肝硬化患者PT、APTT、FIB、TT及D-D参数变化的初步探讨
引用本文:李志方,邓小燕.肝硬化患者PT、APTT、FIB、TT及D-D参数变化的初步探讨[J].广州医药,2006,37(4):47-48.
作者姓名:李志方  邓小燕
作者单位:广州医学院第二附属医院检验科,广州510260
摘    要:目的 研究肝硬化患者凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、血浆纤维蛋白原(FIB)、血浆凝血酶时间(TT)及D-二聚体(D-D)的变化及临床意义.方法 应用全自动血凝仪和全自动生化仪检测各组血浆中PT、APTT、FIB、TT及D-D值.结果 肝硬化患者与对照组比较PT、APTT、TT及D-D均明显延长而FIB则明显下降,两者比较差异有显著性(P<0.01).结论 肝硬化患者血浆凝血及纤溶实验(PT、APTT、FIB、TT及D-D)各参数均有变化,可从多方面客观准确地评价肝硬化患者凝血功能状况及其病情预后.

关 键 词:肝硬化  凝血酶原时间  活化部分凝血酶原时间  血浆纤维蛋白原  血浆凝血酶时间  D-二聚体  参数
收稿时间:05 31 2006 12:00AM
修稿时间:2006-05-31

Exploration on changes of PT, APTT, FIB, TT and D-D in patients with cirrhosis
Li Zhifang, Deng Xiaoyan..Exploration on changes of PT, APTT, FIB, TT and D-D in patients with cirrhosis[J].Guangzhou Medical Journal,2006,37(4):47-48.
Authors:Li Zhifang  Deng Xiaoyan
Institution:The Laboratory Department of the Second Affiliated Hospital of Guangzhou Medical College, Guangzhou 510260
Abstract:Objective To explore the changes and significance of PT,APTT,FIB,TT and D-D in patients with cirrhosis.Methods PT,APTT,FIB,TT and D-D were measure by full-antomatic instrument.Results The PT,APTT,TT and D-D obviously prolong but the FIB obviously descend,those patients indices showed the significant difference in compared with normal control subjects(P<0.01).Conclusion The changes of PT,APTT,FIB,TT and D-D in patients with cirrhosis are determined,these indices can be used to evaluate the coagulation bloods fundtion and prognosis.
Keywords:Cirrhosis  PT  APPTT  FIB  TT  D-D  Index
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