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Repairing neuronal circuits with brain grafts: Where can brain grafts be used as a therapy?
Authors:William J. Freed
Affiliation:Preclinical Neurosciences Section, Neuropsychiatry Branch National Institute of Mental Health, Saint Elizabeths Hospital, Washington, DC 20032, USA
Abstract:Transplanted brain tissues are unlikely to become completely integrated into a mature host brain. This places a limitation upon the types of neuronal circuitry that brain grafts can be used to repair. Brain disorders that may be repairable by brain grafts are those with a loss of unidirectional inputs to anatomically restricted brain regions.
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