Dual-energy perfusion CT of non-diseased lung segments using dual-source CT: correlation with perfusion SPECT |
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Authors: | Yoshie Kunihiro Munemasa Okada Naofumi Matsunaga Yuichi Sano Shohei Kudomi Kazuyoshi Suga Shoji Kido |
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Affiliation: | 1. Department of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi, 755-8505, Japan 2. Department of Radiology, Yamaguchi University Hospital, Ube, Japan 3. Department of Radiology, St Hill Hospital, Ube, Japan 4. Computer-aided Diagnosis and Biomedical Imaging Research Biomedical Engineering, Applied Medical Engineering Science Graduate School of Medicine, Yamaguchi University, Ube, Japan
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Abstract: | Purpose To determine the utility of dual-energy perfusion CT (DEpCT) of non-diseased lung segments, using dual-source CT, in comparison with perfusion single-photon emission computed tomography (SPECT). Materials and methods 28 patients (18 male and 10 female; mean age 63 years; age range 18–86 years) underwent DEpCT and SPECT within a 3-day interval. The presence and location of perfusion defects in each segment of the lungs were evaluated. Results Perfusion defects were noted in 7 of 361 segments (1.9 %) by DEpCT and in 19 of 361 segments (5.3 %) by perfusion SPECT. DEpCT was in good agreement with perfusion SPECT for 338 of 361 segments (93.6 %). Intraobserver agreement was also good, ranging from 93.4 to 93.6 % (κ = 0.64–0.75, p < 0.01). Conclusion For non-diseased lung segments, DEpCT correlated well with SPECT. |
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