Risk factors for the association of intracranial and aortic aneurysms |
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Authors: | N Miyazawa I Akiyama Z Yamagata |
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Institution: | (1) PET Center, Kofu Neurosurgical Hospital, Kofu, Yamanashi, Japan;(2) Department of Neurosurgery, Akiyama Neurosurgical Clinic, Nirasaki, Yamanashi, Japan;(3) Department of Health Science, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan |
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Abstract: | Summary This study investigated the association of intracranial aneurysms and abdominal aortic aneurysms to elucidate the incidence
and independent risk factors for this association. Ultrasonography of the abdominal aorta was performed in 181 patients with
224 intracranial aneurysms. Six patients had suffered subarachnoid haemorrhage and the others had chronic disease or no symptoms.
Magnetic resonance angiography was performed for confirmation if abdominal aortic aneurysm was identified by ultrasonography.
Thirteen patients (7.2%) with 23 intracranial aneurysms had abdominal aortic aneurysms. Univariate analysis demonstrated that
age (p < 0.01), size of intracranial aneurysms (p < 0.001), male sex (p < 0.01), multiplicity of intracranial aneurysms (p < 0.001), history of cerebrovascular diseases (p < 0.05), and current smoking (p < 0.0001) were significantly different between patients with and without this association. Multiple logistic analysis indicated
that age (odds ratio OR] 1.27, 95% confidence interval 1.08–1.48, p < 0.01), multiplicity (OR 22.1, 95% confidence interval 1.83–266.3, p = 0.01), size of intracranial aneurysms (OR 1.30, 95% confidence interval 1.10–0.54, p < 0.01), and current smoking (OR 33.3, 95% confidence interval 2.43–456.7, p = 0.01) were independent risk factors for the association. Patients with intracranial aneurysms who are older males with
multiple or large intracranial aneurysms, and current smokers should be examined for abdominal aortic aneurysms using ultrasonography. |
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Keywords: | : Aortic aneurysm intracranial aneurysm magnetic resonance angiography ultrasonography |
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