| 展望CRISPR/Cas9基因编辑技术在药用植物研究中的应用 |
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| 引用本文： | 胡添源,高伟,黄璐琦. 展望CRISPR/Cas9基因编辑技术在药用植物研究中的应用[J]. 中国中药杂志, 2016, 41(16): 2953-2957 |
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| 作者姓名： | 胡添源 高伟 黄璐琦 |
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| 作者单位： | 首都医科大学 中医药学院, 北京 100069,首都医科大学 中医药学院, 北京 100069,中国中医科学院 中药资源中心 道地药材国家重点实验室培育基地, 北京 100700 |
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| 基金项目： | 国家自然科学基金面上项目（31570358）；贵州省高层次创新人才培养项目（黔科合人才（2015）4033号）；贵州省中药现代化科技产业研究开发专项（黔科合中药字[2013]5005） |
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| 摘 要： | CRISPR/Cas9基因编辑技术是近几年新发现的一种基因组定点编辑技术,该技术已经广泛应用在基因治疗、基因功能研究、动物模型制造、农作物品种改良等领域的研究中。该文简要介绍了CRISPR/Cas9基因编辑技术,并提出了这项技术在药用植物功能基因组学研究、活性成分次生代谢及合成生物学研究、药用植物分子育种研究等方面的应用前景,为开辟药用植物新领域的研究提供了参考。
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| 关 键 词： | 药用植物 CRISPR/Cas9 基因编辑技术 |
| 收稿时间： | 2016-05-05 |
Prospecting application of CRISPR/Cas9 genome editing technology in research of medicinal plants |
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| HU Tian-yuan,GAO Wei and HUANG Lu-qi. Prospecting application of CRISPR/Cas9 genome editing technology in research of medicinal plants[J]. China Journal of Chinese Materia Medica, 2016, 41(16): 2953-2957 |
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| Authors: | HU Tian-yuan GAO Wei HUANG Lu-qi |
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| Affiliation: | School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China,School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China and Key Laboratory of Dao-di Herbs, National Resources Center for Chinses Materia Medica, China Academy of Chinese Medicinal Sciences, Beijing 100700, China |
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| Abstract: | CRISPR/Cas9 genome editing technology is a newly discovered genome editing technology in recent years.It has been widely used in many fields such as gene therapy, gene function research, animal model-making,cropvariety improvement and so on. This article briefly introduces the CRISPR/Cas9 genome editing system, and discusses its potential applications in the research of medicinal plants, including functional genomics studies, secondary metabolism and synthetic biology research of important active components and molecular breeding research. CRISPR/Cas9 genome editing technology provides a new method for the research of medicinal plants. |
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| Keywords: | medicinal plants CRISPR/Cas9 genomeediting technology |
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