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~1H-MRS磁共振波谱分析对海马硬化诊断的评价
引用本文:罗超,陈元媛,赵林,宋佳.~1H-MRS磁共振波谱分析对海马硬化诊断的评价[J].临床军医杂志,2011,39(1).
作者姓名:罗超  陈元媛  赵林  宋佳
作者单位:解放军广州军区武汉总医院,放射影像科,湖北,武汉,430070
摘    要:目的分析原发性颞叶癫痫与海马硬化之间的关系,探讨磁共振波谱成像(1H-MRS)在海马硬化早期诊断中的应用价值。方法回顾性分析30例经手术证实的海马硬化患者的临床表现、1H-MRS资料,重点分析1H-MRS的NAA、Cr、Cho波峰特点。结果 1H-MRS发现异常28例(93%),2例在MRI及1H-MRS均未见异常。结论 1H-MRS可对海马硬化或伴有海马胶质细胞增生者进行早期诊断,提高了海马硬化诊断的敏感性。

关 键 词:癫痫  颞叶  海马硬化  磁共振成像

Evaluation of 1H magnetic resonance spectroscopy in the diagnosis of hippocampai sclerosis
Luo Chao,Chen Yuan-yuan,Zhao Lin,Song Jia.Evaluation of 1H magnetic resonance spectroscopy in the diagnosis of hippocampai sclerosis[J].Clinical Journal of Medical Officer,2011,39(1).
Authors:Luo Chao  Chen Yuan-yuan  Zhao Lin  Song Jia
Institution:Luo Chao,Chen Yuan-yuan,Zhao Lin,Song Jia(Department of Radiology,Wuhan General Hospital of Guangzhou Command,PLA,Wuhan Hubei 430070,China)
Abstract:Objective To investigate the relationship between primary temporal lobe epilepsy and hippocampal sclerosis(HS).Analysis the value of magnetic resonance spectroscopy(1H-MRS)in the diagnosis of HS.Methods Retrospectively analyzed the clinical symptoms、1H-MRS findings in thirty patients with pathology proved HS.The parameters of 1H-MRS included peak characteristics of NAA、Cr and Cho.Results Abnormal parameters were found in twenty-eight patients(93%) on 1H-MRS.No abnormality was found in two patients on MRI and 1H-MRS.Conclusion 1H-MRS is a sensitive method to diagnosing early HS and improving the sensitivity of HS.
Keywords:epilepsy  temporal lobe  hippocampus sclerosis  magnetic resonance spectroscopy  
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