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Central nervous system involvement in Whipple's disease
Authors:Dr. B. Ludwig  J. Bohl  G. Haferkamp
Affiliation:(1) Department of Neuroradiology, University Hospital, Langenbeckstraße 1, D-6500 Mainz, Federal Republic of Germany;(2) Department of Neuropathology and Neurology, University Hospital, Langenbeckstraße 1, D-6500 Mainz, Federal Republic of Germany
Abstract:Summary A case of Whipple's disease is presented manifesting itself predominantly with neurological and mental symptoms but without gastrointestinal complaints. Although the first cranial CT in the fourth year of the disease was normal, the second, 1.5 years later, revealed intensive hypodensity of the white matter and cortical enhancement. CT findings are compared with autopsy results and a review of the pertinent literature is given.
Keywords:Whipple's disease  Central nervous system involvement  CT findings  Autopsy results
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