链霉蛋白酶与利多卡因胶浆联用提高超声内镜检查清晰度的研究

目的评价检查前联合使用链霉蛋白酶和利多卡因胶浆对缩短超声胃镜操作时间和改善内镜、超声图像方面的效果。方法将超声内镜受检者80例随机分为A、B组，每组40例。A组于检查前15min口服利多卡因胶浆10ml；B组于检查前30rain口服含10000单位链霉蛋白酶和1g碳酸氢钠的温开水50ml，并于检查前15min口服利多卡因胶浆10ml。记录总操作时间，并对超声胃镜下胃内黏液附着量及超声图像的清晰度进行评分。结果A组操作时间长于B组（15．5±3．0）min比（12．3±2．3）min，P〈0．001]，B组内镜和超声内镜图像视野清晰度均优于A组。结论链酶蛋白酶和利多卡因胶浆联用可有效去除胃内黏液艉高超声内镜检查成像质量。

A study of the combined use of pre-medication with pronase and lidocaine hydrochloride mucilage for improving image visibility in endoscopic ultrasonography

Objective To test whether pre-medication with pronase and lidocaine hydrochloride mu- cilage can reduce the procedure time and improve image visibility in endoscopic uhrasonography （EUS）. Methods A total of 80 patients who accepted EUS were randomly assigned to group A to have oral lidocaine hydrochloride mucilage 10 ml 15 minutes before the examination or group B to have oral 10 000 unit pronase with 1 gram sodium bicarbonate plus warm water up to 50 m｜ 30 minutes before EUS and oral 10 ml lidocaine hydrochloride mucilage 15 minutes before the procedure. The total checking time, EUS image visibility scores （ range 1-4） were recorded. Results The operation time of group A （ 15.5 ± 3.0 minutes） was sig- nificantly longer than that of group B （ 12. 3 ±2. 3 minutes, P 〈0. 001 ）. The EUS images from group B had higher visibility scores than group A （P 〈 0. 05）. Conclusion Pre-medication with pronase and lidocaine hydrochloride mucilage can reduce the procedure time and improve image visibility in EUS.