Biological mechanisms underlying the relationship between stress and smoking: state of the science and directions for future work |
| |
Authors: | Richards Jessica M Stipelman Brooke A Bornovalova Marina A Daughters Stacey B Sinha Rajita Lejuez C W |
| |
Affiliation: | a Department of Psychology, Center for Addictions, Personality, and Emotion Research (CAPER), University of Maryland, 2103 Cole Activities Building, College Park, MD 20742, USA b The National Cancer Institute, Rockville, MD, USA c Department of Psychology & Department of Mental Health Law and Policy, University of South Florida, Tampa, FL 33620, USA d Department of Behavioral and Community Health, School of Public Health, University of Maryland, College Park, MD, USA e Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA f Yale Child Study Center, New Haven, CT 06520-7900, USA |
| |
Abstract: | Theories of addiction implicate stress as a crucial mechanism underlying initiation, maintenance, and relapse to cigarette smoking. Examinations of the biological stress systems, including functioning of the hypothalamic-pituitary-adrenal (HPA) axis and the autonomic nervous system (ANS), have provided additional insights into the relationship between stress and smoking. To date, convergent data suggests that chronic cigarette smoking is associated with alterations in HPA and ANS functioning; however, less is known about the role of HPA and ANS functioning in smoking initiation and relapse following cessation. In order to organize existing findings and stimulate future research, the current paper summarizes the available literature on the roles of HPA axis and ANS functioning in the relationship between stress and cigarette smoking, highlights limitations within the existing literature, and suggests directions for future research to address unanswered questions in the extant literature on the biological mechanisms underlying the relationship between stress and smoking. |
| |
Keywords: | HPA axis Stress Cortisol Autonomic nervous system Smoking Nicotine dependence |
本文献已被 ScienceDirect PubMed 等数据库收录! |
|