组织工程神经支架的研究进展

周围神经损伤在临床上非常多见,周围神经损伤给患者带来了高致残率,并给社会及患者家庭带来了巨大的经济负担.这些都使得周围神经损伤成为全球所面临的严峻的健康问题之一.目前,随着神经组织工程的发展,为临床上神经缺损的修复带来了新的希望.神经支架在修复神经缺损方面具有重要作用,可为神经细胞提供暂时的支持、黏附、生长环境,促进神经缺损的修复.就神经支架的分类、特性、应用及存在的问题和发展趋势作一综述.

Development of nerve scaffold in tissue engineering

Peripheral nerve injury is very common in clinics. It has brought the patients with high rate of disability and huge economic burden and become one of serious health problems in the world. Nowadays, with the development of nerve tissue engineering, it provides new method for surgical procedures of nerve defects repair.The nerve scaffold plays a vital role in repairing nerve defects. It can provide temporary support for nerve cells to grow,adhere and to form structures. This review aims at introducing classification, properties and the applications of the nerve scaffolds for tissue engineering. Future development of the nerve scaffolds and remaining problems are discussed as well.