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动脉粥样硬化易损斑块的生物学标志物
引用本文:冯刚,胡长林. 动脉粥样硬化易损斑块的生物学标志物[J]. 国际脑血管病杂志, 2010, 18(6): 696-701. DOI: 10.3760/cma.j.issn.1673-4165.2010.09.012
作者姓名:冯刚  胡长林
作者单位:重庆医科大学附属第二医院神经内科,400010;
摘    要:多种生化分子参与了动脉粥样硬化的发生发展、斑块失稳定性和破裂过程.因此,寻找能识别易损斑块和预测斑块破裂风险的血清生物学标志物,对临床工作具有重要的指导意义.文章综述了近年来有关易损斑块生物学标志物的研究进展.

关 键 词:动脉粥样硬化   生物学标志物   炎症   细胞凋亡   

Biological markers of vulnerable atherosclerotic plaques
FENG Gang,HU Chang-lin. Biological markers of vulnerable atherosclerotic plaques[J]. International Journal of Cerebrovascular Diseases, 2010, 18(6): 696-701. DOI: 10.3760/cma.j.issn.1673-4165.2010.09.012
Authors:FENG Gang  HU Chang-lin
Abstract:There are a number of serum biomarkers related with the process of the pathogenesis,destabilization and rupture of the atherosclerotic plaque.And thus,it is fairly important in clinical practice to identify vulnerable plaque and predict plaque rupture by detecting the expression of the serum biomarkers.This review aims at giving an overview on recent emerging biomarkers that are related to vulnerable plaque.
Keywords:AtherosclerosisBiological markersInflammationApoptosis
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