痛风的影像学研究进展

影像学检查可以帮助临床医师评价痛风.X线成像只能显示慢性痛风进展期的典型变化.CT可能是评价痛风骨改变和痛风石的最好方法,双源CT可以评估全身周围关节的尿酸盐总沉积量.MRI适合评估软组织、滑膜厚度和炎性反应,对痛风的早期病变敏感性很高,也能够较好的显示痛风石.超声检查可以评价软骨、软组织、尿酸盐沉积和滑膜炎性反应.核医学有助于在细胞和分子层面理解痛风性关节炎的发病机制.

Recent progress of imaging in gout

Imaging is a helpful tool for clinicians to evaluate gout. Plain radiographs show typical changes only in advanced chronic gout. Computed tomography may best evaluate bone changes and tophi. Dual energy CT can measure the total urate burden in general periphery joints. Magnetic resonance imaging is suitable to evaluate soft tissues,synovial membrane thickness,and inflammatory changes,which is also sensitive to early change of gout,and even well show the tophi. Ultrasonography may be used in evaluation of cartilage, soft tissues, urate crystal deposition, and synovial membrane inflammation. Nuclear medicine may be helpful to investigate the pathogenesis of gouty arthritis in the field of cell and molecule.