| 棕色脂肪组织的形成及其作用机制 |
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| 引用本文： | 唐松涛,章秋. 棕色脂肪组织的形成及其作用机制[J]. 国际内分泌代谢杂志, 2010, 31(6): 180-183. DOI: 10.3760/cma.j.issn.1673-4157.2011.03.012 |
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| 作者姓名： | 唐松涛 章秋 |
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| 作者单位： | 安徽医科大学第一附属医院内分泌科,合肥,230022; |
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| 摘 要： | 人体内脂肪组织分为棕色脂肪组织(BAT)和白色脂肪组织(WAT).它们在组织形态和生理作用上存在较大差异,BAT主要在寒冷环境或交感神经兴奋下参与产热过程,而WAT主要以甘油三酯的形式储存多余能量.通过对BAT形成和作用机制的研究发现,两种脂肪组织的起源不同,并且揭示出部分细胞因子与BAT形成及活化之间的复杂关系,从而为肥胖及其相关疾病的防治提供了新的途径.
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| 关 键 词： | 棕色脂肪组织 肥胖 能量消耗 细胞因子 |
The formation and functional mechanism of brown adipose tissue |
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| TANG Song-tao,ZHANG Qiu. The formation and functional mechanism of brown adipose tissue[J]. International JOurnal of Endocrinology and Metabolism, 2010, 31(6): 180-183. DOI: 10.3760/cma.j.issn.1673-4157.2011.03.012 |
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| Authors: | TANG Song-tao ZHANG Qiu |
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| Abstract: | The adipose tissue in human body can be divided into brown adipose tissue (BAT) and white adipose tissue (WAT). They have many differences in morphology and physiological functions. BAT mainly involves in the production of heat in response to cold and sympathetic nervous system activation,while WAT stores excess energy as triacylglycerols. Researches of formation and functional mechanism of BAT show that these two kinds of adipose tissue derived from different progenitors and revealed the complex relationship between several cytokines and BAT. These findings provide another precaution and treatment for human obesity and its related diseases. |
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| Keywords: | Brown adipose tissueObesityEnergy expenditureCytokine |
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