急性冠脉综合征高龄患者PCI术后影响预后危险因素临床分析

目的:分析影响急性冠脉综合征高龄患者PCI术后预后的危险因素。方法:选取3年来我科住院72例接受PCI术的急性冠脉综合征患者,按年龄分为:高龄组,年龄≥75岁,共36例;低龄组,年龄<75岁,共36例。分析高龄患者PCI术后的HbA1c、NT-proBNP、血小板聚集率(PAGR)与随访1年后LVEF、LVEDd值的相关性。比较两组的主要不良心脏事件(MACE),即再梗塞率及死亡率之间的差异。结果:高龄患者的NT-proBNP、PAGR与LVEF值呈负相关关系,相关系数为-0.891和-0.901,与LVEDd值呈正相关关系,相关系数为0.857和0.924。而HbAlc与LVEF、L-VEDd值无明显相关性。两组的MACE(再梗塞率及死亡率)部存在差异性,P值分别为0.0148与0.0254。结论:急性冠脉综合征高龄患者PCI术后MACE较低龄患者发生率高,且心脏功能与NT-proBNP及PAGR有相关性。

The Clinic Analysis of Risk Factors Effecting on Prognosis of Aged Patients with Acute Coronary Syndrome Post-percutaneous Coronary Intervention

Objective:To analyze the risk factors affecting on prognosis of aged patients with acute coronary syndrome(ACS) post-PCI operation.Methods:A total of 72 patients with ACS in our hospital received PCI operation were divided into two groups,senility group(age>75) and young group(age<75),each group involved 36 patients,according to the age.The factors of HbA1c,NT-proBNP and platelet aggregation rate(PAGR) were ananlyzed the correlation to the value of LVEF and LVEDd after 1 year follow-up.And major adverse cardiac events(MACE),such as recurrent MI and mortality death rate,were compared between two groups.Results:The negative correlation coefficients of NT-proBNP and PAGR with LVEF were -0.891 and -0.901,respectively.The positive correlation coefficients of NT-proBNP and PAGR with LVEF were 0.857 and 0.924,respectively.The rate of MACE was different between two groups,and the values of P were 0.0148 and 0.0254,respectively.Conclusion:The rate of MACE in aged patients with ACS received PCI operation was higher than young patients,and cardie fuction had correlation to NT-proBNP and PAGR.