沙美特罗联合布地奈德治疗哮喘37例

目的 观察沙美特罗联合布地奈德治疗哮喘的疗效.方法 将74例哮喘患者随机均分成治疗组和对照组,治疗组在常规治疗基础上加用布地奈德联合沙美特罗(舒利迭)干粉剂(50 μg/250μg)吸入,每日2次;对照组在常规治疗基础上加用布地奈德吸入,200 μg/次,每日2次.两组疗程均为15 d,并采用哮喘症状评分、肺功能及治疗后3个月进行哮喘测试控制量表(ACT)评分.结果 两组在哮喘症状评分、肺功能和哮喘测试控制量表评分上均有改善,而治疗组较对照组改善更明显(P＜0.01).结论 沙美特罗联合布地奈德治疗哮喘具有较好控制效果,且疗效好、经济、方便,值得临床推广应用.

Effect of Salmeterol Combined Budesonide in Treating 37 Cases of Asthma

Objective To investigate the effect of combination of salmeterol and budesonide in the treatment of asthma.Methods Seventy-four cases of asthma were randomly divided into the treatment group and the control group,37 cases in each group.The treatment group received the conventional therapy plus budesonide combined salmeterol（Seretide） dry powder,50 μg/250 μg inhalation,twice a day.The control group was treated by conventional therapy plus budesonide aerosol inhalation,200 μg per time,twice daily.The treatment course in both two groups was 15 d.The effects were evaluated by the asthma symptom scores,lung function and the ACT scoring after 3-month treatment.Results The asthma symptom score,lung function and ACT score in the two groups all were improved.But the improvement in the treatment group was more significant than that in the control group with statistical significance（P 0.01）.Conclusion The combination therapy of salmeterol and budesonide has better control effects on asthma with good efficacy,convenience and economy,which is consistent with the clinical application and dissemination.