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| 低分子肝素用于小儿原发性肾病综合征的疗效观察 | |
| 引用本文： | 黄惠梅,王焱,李飞,包瑛. 低分子肝素用于小儿原发性肾病综合征的疗效观察[J]. 中国医药导刊, 2011, 13(8): 1380-1381 |
| 作者姓名： | 黄惠梅 王焱 李飞 包瑛 |
| 作者单位： | 1. 西安市儿童医院肾内科,西安,710002 2. 西安市第九医院儿科,西安,710054 3. 陕西省肿瘤医院普外科,西安,710061 |
| 摘 要： | 目的:观察低分子肝素(LMWH)对小儿原发性肾病综合征(PNS)的临床疗效。方法:将60例小儿PNS分为LMWH治疗组和对照组即常规治疗组,予以比较。结果:LMWH治疗组较对照组4周后血清白蛋白明显增高,总胆固醇明显下降(P<0.01),尿蛋白明显下降,尿蛋白转阴时间明显缩短(P<0.05)。结论:LMWH治疗后可明显改善小儿PNS的高凝状态,对其疾病的尽快缓解有重要意义,且副作用少,出血风险小,其安全性值得临床推广使用。 |
| 关 键 词： | 肾病综合征 低分子肝素 高凝状态 |
Effect Observation of Nadroparin Calcium Functioning on the Children Primary Nephrotic Syndrome |
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| Affiliation: | Huang Hui-mei1,Wang Yan2,Li Fei3,et al. (1 Nephrology Department,Xi’an Children Hospital,Xi’an 710002,China;2 Paediatrics Department,Xi’an Ninth Hospital,Xi’an 710054; 3 General Surgery Department,Shanxi Provincial Tumour Hospital,Xi’an 710061,China) |
| Abstract: | Objective:Observing the clinical effects of nadroparin calcium(LMWH) functioning on children primary nephrotic syndrome(PNS ).Methods:Making a comparison in 60 samples which divided in to LMWH treating group and normal treating group. Results:LMWH treating group increase in the amount of seralbumin and obviously found the descending of cholesterol(P<0.01) and descending of urin protein,and also the shortening of the integration time of unrin protein(P<0.05) with the comparison to normal treating group after 4 weeks.Conclusion:LMWH can obviously improve the Hypercoagulability of Children PNS with less side effect and less risk of bleeding.It is highly rated in the clinical treatment because of its high safety. |
| Keywords: | Nephrotic syndrome Nadroparin calcium Hypercoagulability |
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