189例慢性胰腺炎诊治分析

目的 总结慢性胰腺炎的诊断和治疗经验。方法 回顾性分析本院1983年－1999年8月收治的189例慢性胰腺炎病例资料。结果 本组患者平均年龄为48．4岁,发病高峰年龄为40－60岁;患者性别比例,男：女为2．1：1。发病1年内确诊率为51．3％,5年确诊率80．4％。CT和逆行胰胆管造影检查（ERCP）诊断阳性率较高,分别为71．9％者因胰瘘、腹腔感染、败血症于术后第7天死亡。术后98％的患者主诉腹痛明显减轻。结论 慢性胰腺炎早期诊断有一定困难,手术时机的掌握和手术方法的选择对于患者生存质量和疾病进程的控制至关重要。

Diagnosis and treatment of one hundred and eighty-nine patients with chronic pancreatitis

OBJECTIVE: To summarize the experience of the diagnosis and therapy of chronic pancreatitis (CP). METHODS: 189 patients with chronic pancreatitis confirmed surgically from 1983 to Aug 1999 admitted in our hospital were retrospectively studied. RESULTS: Of all 189 patients, the average age was forty-eight years old. The ratio of male to female is 2.1:1. The proportion of confirmed diagnosis to CP is 51.3% within one year and 80.4% within the first five years. The positive rate for diagnosis was 71.9% by CT and 76.9% by ERCP respectively. The positive rate of PABA was 69.7%. While 136(72%) patients received operations, the rate of complication was low. One patient died of infection after pancreatic fistula at the seventh day after surgery, and 97.8% of patients suffered less pain. CONCLUSIONS: The early diagnosis of CP is difficult. As a delicate operation program set at appropriate time is of vital importance for modifying the course of the disease and improving patients' life quality.