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2003~2006年866例加替沙星致不良反应报告分析
引用本文:章梅华,卢晓阳,张国兵.2003~2006年866例加替沙星致不良反应报告分析[J].中国药房,2007,18(35):2778-2779.
作者姓名:章梅华  卢晓阳  张国兵
作者单位:浙江大学医学院附属第一医院药剂科,杭州市,310003
摘    要:目的:了解加替沙星致不良反应的发生特点。方法:对2003年10月30日~2006年10月30日浙江省药品不良反应监测中心收集的866例加替沙星引发的不良反应报告进行Excel列表分析。结果:皮肤及其附件、消化系统、全身性及神经系统损害是加替沙星常见的不良反应,多数症状轻微,但其存在潜在的、损害人体重要器官的不良反应,如糖代谢紊乱等。结论:加强不良反应的监测工作,以减少和避免不良反应的发生。

关 键 词:加替沙星  药品不良反应  血糖紊乱  分析
文章编号:1001-0408(2007)35-2778-02
修稿时间:2007年1月21日

Adverse Drug Reactions Induced by Gatifloxacin: Analysis of 866 Cases During 2003~2006
ZHANG Meihua,LU Xiaoyang,ZHANG Guobing.Adverse Drug Reactions Induced by Gatifloxacin: Analysis of 866 Cases During 2003~2006[J].China Pharmacy,2007,18(35):2778-2779.
Authors:ZHANG Meihua  LU Xiaoyang  ZHANG Guobing
Abstract:OBJECTIVE:To study the characteristics of adverse drug reactions(ADR) induced by gatifloxacin.METHODS:A total of 866 ADR cases induced by gatifloxacin collected in Zhejiang ADR Monitoring Center between Oct.30,2003 and Oct.30,2006 were analyzed with Excel.RESULTS:The common ADR induced by gatifloxacin were lesions of skin and appendages,gastro-intestinal system,systemic and nervous system.Most of the cases were slight in symptoms,but gatifloxacin could also induce severe ADR such as dysglycemia etc that resulting in potential risks to vital human organs.CONCLUSION:ADR monitoring should be emphasized when using gatifloxacin so as to decrease or avoid the occurrence of ADR.
Keywords:Gatifloxacin  Adverse drug reaction  Dysglycemia  Analysis
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