| 右美托咪定抑制瑞芬太尼诱发痛觉过敏的研究进展 |
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| 引用本文： | 张耀贤,张中军. 右美托咪定抑制瑞芬太尼诱发痛觉过敏的研究进展[J]. 广州医药, 2014, 45(1): 83-85 |
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| 作者姓名： | 张耀贤 张中军 |
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| 作者单位： | 张耀贤 (暨南大学第二临床医学院,深圳市人民医院麻醉科,深圳,518000)； 张中军 (暨南大学第二临床医学院,深圳市人民医院麻醉科,深圳,518000)； |
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| 摘 要： | 瑞芬太尼作为一种人工合成的超短效阿片类药物,广泛应用于临床麻醉,但持续输注瑞芬太尼可诱发痛觉过敏。右美托咪定是一种高选择性的α2肾上腺素能受体激动剂,具有镇静、抗焦虑和镇痛等作用。近年有研究报道右美托咪定可抑制瑞芬太尼诱发的痛觉过敏,本文将就相关研究进行综述。
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| 关 键 词： | 右美托咪定 瑞芬太尼 痛觉过敏 |
Research progress on dexmedetomidine inhibit hyperalgesia induced byremifentanil |
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| Zhang Yaoxian,Zhang Zhongjun. Research progress on dexmedetomidine inhibit hyperalgesia induced byremifentanil[J]. Guangzhou Medical Journal, 2014, 45(1): 83-85 |
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| Authors: | Zhang Yaoxian Zhang Zhongjun |
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| Affiliation: | .( Department of Anesthesiology, Shenzhen people＇s hospital, second clinical medical college of Jinan university, Shenzhen 518000, China) |
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| Abstract: | Remifentanil is a synthetic ultra-short-effect opioid drugs. It has been widely used in clinical anesthesia. However, a continuous infusion of remifentanil may induce hyperalgesia. Dexmedetomidine is a highly selective α2-ad- renoceptor agonist, providing sedation, antianxi-ety and analgesia. Recent studies have reported dexmedetomidine can inhibit hy- peralgesia induced by remifentanil, the relevant studies were reviewed. |
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| Keywords: | Dexmedetomidine Remifentanil Hyperalgesia |
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