Performance and utility of a rapid diagnostic test for cholera: notes from Haiti |
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Authors: | Jacques Boncy Emmanuel Rossignol Georges Dahourou Marisa Hast Josiane Buteau Magalie Stanislas Daphne Moffett Cheryl Bopp S Arunmozhi Balajee |
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Institution: | 1. National Public Health Laboratory, Ministry of Public Health and Population, Port-au-Prince, Haiti;2. Centers for Disease Control and Prevention, Port au Prince, Haiti;3. Division of Global Disease Detection and Emergency Response, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA;4. Division of Foodborne, Water and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA |
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Abstract: | The present study details work done at the National Public Health Laboratory in Haiti (LNSP), comparing the results of a cholera rapid diagnostic test (RDT) with culture-based methods. As of October 21, 2011, 644 specimens were tested by both RDT and culture-based method at the LNSP. The sensitivity and specificity of RDT were 95% and 80%, respectively, with a positive predictive value of 89% and negative predictive value of 91%. In resource-limited settings, the RDT has good utility and should be considered as part of the laboratory testing algorithm. |
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Keywords: | Cholera RDT Crystal VC |
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