Carbapenemase-producing Enterobacteriaceae during 2011-12 in the Bolzano area (Northern Italy): increasing diversity in a low-endemicity setting |
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| Authors: | Richard Aschbacher Tommaso Giani Daniele Corda Viola Conte Fabio Arena Valentina Pasquetto Katia Scalzo Maira Nicoletti Gian Maria Rossolini Elisabetta Pagani |
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| Affiliation: | 1. Laboratory of Microbiology and Virology, Bolzano Health District, Bolzano, Italy;2. Department of Medical Biotechnologies, University of Siena, Siena, Italy;3. Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy;4. Clinical Microbiology and Virology Unit, Department of Laboratory Medicine, Careggi University Hospital, Florence, Italy |
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| Abstract: | The recent (2011–2012) distribution of carbapenemase determinants in Enterobacteriaceae was studied in the Bolzano area (Northern Italy). Low proportions of carbapenemase producers were found for Escherichia coli (0.2%), Citrobacter freundii (1.1%), Klebsiella pneumoniae (1.3%), Klebsiella oxytoca (1.6%) and Enterobacter spp (1.8%). Although VIM-1 remained the most common carbapenemase, the emergence of K. pneumoniae producing KPC-3 and of E. coli producing OXA-48 was observed. Of concern is the spread of the hyperepidemic strains E. coli ST131 producing VIM-1 and K. pneumoniae ST258 producing KPC-3. Low essential and category agreements between the reference broth microdilution and commercial methods were observed for carbapenems. |
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| Keywords: | Enterobacteriaceae Carbapenemases VIM KPC OXA-48 |
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