Impact of identification of Streptococcus dysgalactiae subspecies equisimilis from throat cultures in an adult population |
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Authors: | Amanda T. Harrington Jill E. Clarridge III |
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Affiliation: | VA Puget Sound Health Care System, Seattle, WA 98108, USA; University of Washington, Seattle, WA 98108, USA |
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Abstract: | Streptococcus dysgalactiae subspecies equisimilis (SDSE) are isolated from the throat of patients with pharyngitis, although the clinical significance remains debated. We sought to determine the incidence and association with pharyngitis of SDSE in an adult veteran population. Organisms were phenotypically identified to subspecies and Lancefield group, with selective 16S rRNA gene sequencing. From 833 throat cultures, the overall frequency of SDSE was 3.4% (64% group C and 36% group G) as compared to 8.6% for S. pyogenes (GAS). SDSE was described as a large colony in only 29% of the original culture evaluations by bench technologists, and clinical symptoms were similar for GAS and SDSE. Laboratory algorithms that are limited to identification of only GAS or are based on Lancefield group or visual identification of “large-colony type” β hemolytic Lancefield group C and G streptococci may be missing or misidentifying SDSE along with Anginosus group streptococci. |
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Keywords: | Pharyngitis Streptococcus dysgalactiae subspecies equisimilis Throat culture |
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