乳腺叶状肿瘤30例诊断与治疗分析

目的 探讨乳腺叶状肿瘤的疗效。方法 对经手术和病理诊断确诊的30例乳腺叶状肿瘤的临床资料进行回顾性分析。结果 30例患者中良性叶状肿瘤16例，交界性叶状肿瘤9例，恶性5例。行局部肿块切除8例，单纯乳房切除术8例，改良根治术13例，姑息性肿块切除术1例。其中20例获随访1～24年，随访期间死亡1例，其余患者均存活，其中4例因肿瘤复发再行乳房单纯切除或改良根治术。结论 手术方式的选择对预后影响较大，扩大的局部切除或单纯乳房切除为推荐术式。

Diagnosis and managment of 30 cases of phyllodes tumor of breast

Objective To explore the diagnosis and treatment of phyllodes tumor of the breast. Methods Clinical data from 30 patients with phyllodes tumor confirmed surgically and pathologically were analyzed retrospectively. Results Of the 30 cases of phyllodes tumor, there were 16 cases of benign tumor, 9 cases of borderline tumor and 5 cases of malignant tumor according to the standard histological criteria. Local mass excision, total mastectomy, modified radical mastectomy and tumor mass excision were performed in 8, 8 and 13 patients, and 1 patient, respectively. A follow up of 20 cases for 1-24 years found 1 death, but all the others survived. Four patients out of the 20 patients underwent total mastectomy or modified radical mastectomy due to tumor recurrence. Conclusion The preoperative diagnosis of phyllodes tumor is difficult. Intraoperative frozen section examination of the suspicious lesions should be conducted. Multiple slices of the specimen should be performed. Surgical options are closely associated with the prognosis. Wide local excision or total mastectomy is recommended in surgical options.