大面积脑梗死52例临床分析

目的提高大面积脑梗死的早期诊断和治疗水平,降低死亡率及病残率。方法对52例大面积脑梗死患者的病因、临床表现及梗死范围等进行总结分析。结果存活43例,死亡9例,病死率为17.3%。结论高血压动脉粥样硬化血栓形成、冠心病伴心房颤动致心源性栓塞是大面积脑梗死的主要病因。脑水肿所致的脑疝是大面积脑梗死早期死亡的直接原因。头颅CT或MRI检查能帮助大面积脑梗死获得早期诊断。综合治疗能降低大面积脑梗死的死亡率及病残率。

Clinical study of large cerebral infarction in 52 cases

[Objective] To improve early diagnosis and treatment and decrease the mortality rate and disability rate in large cerebral infaction. [Methods] The etiological factor, clinical situation and infracted range of large cerebral infarction in the 52 eases were analyzed respectively. [Result] In our samples, 43 patients were survived and 9 died. The fatality rate was 17.3%. [Conclusions] The main etiological factor of large cerebral infaction was the thrombosis caused by hypertention and atherosclerosis and cardiogenic embolism caused by coronary heart disease accompanied atrial fibrillation. The death of large cerebral infaction could be directly attributed to cerebral hernia caused by cerebral edema. Brain CT scan or MRI can provide the objective basis for the early diagnosis of large cerebral infarction. Colligation treatment can reduce the mortality rate and disability rate of large cerebral infaction.