Lipid peroxidation level in the focus of compression ischemia in the cerebral cortex of rats |
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| Authors: | A M Dupin I V Barskov I V Viktorov A N Erin |
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| Institution: | (1) Research Institute of Clinical Psychiatry, Research Center of Mental Health, Russian Academy of Medical Sciences, Moscow;(2) Research Institute of the Brain, Russian Academy of Medical Sciences, Moscow |
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| Abstract: | Pathomorphological changes in a focus of ischemia, the level of lipid peroxidation (as indicated by the content of products
reacting with thiobarbituric acid), and the postischemic levels of adenyl nucleotides and tissue lipids were studied in rats
with focal compression ischemia of the cerebral cortex. An increased level of the TBA-reactive products paralleled by a reduction
of the concentrations of adenyl nucleotides and tissue lipids was found to be in clear-cut correlation with the processes
of neuronal injury and death and with subsequent repair phenomena in the focus of cortical ischemia.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, N
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12, pp. 589–590, December, 1994
Presented by O. S. Adrianov, Member of the Russian Academy of Medical Sciences |
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| Keywords: | ischemia brain lipid peroxidation |
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