| 喉癌患者血清中白细胞介素-18的检测意义 |
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| 引用本文： | 石莹,陈素莲,杨琦,夏俊,陈治文. 喉癌患者血清中白细胞介素-18的检测意义[J]. 蚌埠医学院学报, 2007, 32(2): 135-136 |
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| 作者姓名： | 石莹 陈素莲 杨琦 夏俊 陈治文 |
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| 作者单位： | 蚌埠医学院 生物化学与分子生物学教研室, 安徽 蚌埠 233030 |
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| 摘 要： | 目的: 探讨血清白细胞介素-18(IL-18)的变化与喉癌的关系。方法: 采用双抗体夹心ELISA法检测22例喉癌患者(喉癌组)和10名健康者(对照组)血清中IL-18的含量。结果: 喉癌组血清IL-18含量为(68.44±39.42)pg/ml,明显高于对照组(28.47±2.29)pg/ml (P<0.001)。结论: 喉癌患者血清IL-18含量增高,可作为喉癌辅助诊断及观察患者病情变化的一项重要生化指标。
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| 关 键 词： | 喉肿瘤 白细胞介素-18 酶联免疫吸附测定 |
| 文章编号： | 1000-2200（2007）02-0135-02 |
| 收稿时间： | 2006-02-24 |
| 修稿时间： | 2006-02-24 |
Significance of serum level of interleukin-18 in laryngeal cancer |
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| SHI Ying,CHEN Su-lian,YANG Qi,XIA Jun,CHEN Zhi-wen. Significance of serum level of interleukin-18 in laryngeal cancer[J]. Journal of Bengbu Medical College, 2007, 32(2): 135-136 |
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| Authors: | SHI Ying CHEN Su-lian YANG Qi XIA Jun CHEN Zhi-wen |
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| Affiliation: | Department of Biochemistry and Molecular Biology, Bengbu Medical College, Bengbu 233030, China |
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| Abstract: | Objective: To investigate the serum level of interleukin(IL)-18 in laryngeal cancer.Methods: The IL-18 concentration in sera was measured in 22 patients with laryngeal cancer,and 10 health control subjects by enzyme-linked immunosorbent assay(ELISA).Results: The concentration of IL-18 in patients with laryngeal cancer[(68.44±39.42)pg/ml] was significantly higher than that of health control subjects[(28.47±2.29)pg/ml](P<0.001).Conclusions: The IL-18 is higher in patients with laryngeal cancer.The concentration of IL-18 may be an important biochemistry predictive sign in assistant diagnoses and monitoring the changes in patients with laryngeal cancer. |
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| Keywords: | laryngeal neoplasms interleukin-18 enzyme-linked immunosorbent assay |
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