92例老年患者尿路感染致病菌及其耐药性分析

目的：研究老年人尿路感染临床分离菌的耐药情况。方法：采用纸片扩散法对1999年1月—2004年1月老年人尿路感染的92例患者致病菌及其耐药性进行临床观察、分析。结果：92例患者共培养出致病菌13种共100株，G^-杆菌中大肠埃希氏菌、克雷伯氏菌和变形杆菌对头孢噻肟、头孢曲松耐药率低于40％，对丁胺卡那霉素耐药率均低于40％，对阿莫西林-舒巴坦的耐药率均大于50％，G^＋球菌中葡萄球菌对于头孢噻肟钠耐药率不超过20％，大多数G^-杆菌和G’球菌对喹诺酮类的耐药率达到70％以上。结论：老年人尿路感染的细菌耐药性严重、应定期监钡4细菌的耐药趋势，以指导用药。

An Analysis of Pathogen and Drug-tolerance in 92 Senile Patients with Urinary Tract Infection

Objective: To determine the pathogen in urinary tract infection in senile patients and its antibiotic resistance.Methods: 92 patients with urinary tract infection between Jan 1999 and Jan 2004 were included in this study.Among them the pathogen and drug-tolerance were detected by paper diffusion method.Results: 13 species including 100 strains pathogen were found in our samples.Less than 40% resistant rate existed in Escherichia coli,klebsiella pneumoniae and bacillus proteus vs Cefotaxime,Ceftriaxone and Amikacin,more than 50% in resistance of Amoxillin.Less than 20% resistant rate was in staphylococcus vs Cefotaxime.The resistant rate of most G-bacilli and G+ cocci against to Aquamox was >70%.Conclusions: drug-tolerance existing in senile patients with urinary tract infection is a severe problem.It is necessary to detect the drug-tolerance in clinic.