Acute pancreatitis induced by ifosfamide therapy |
| |
Authors: | Garg Rajan Agarwala Sandeep Bhatnagar Veereshwar |
| |
Institution: | Department of Pediatric Surgery, All India Institute of Medical Sciences, New Delhi-110029, India |
| |
Abstract: | Ifosfamide used in the treatment of pediatric solid tumors is known to have serious adverse effects, including acute pancreatitis, a rare complication of therapy. This report describes a young girl who developed acute pancreatitis while being treated for recurrent Wilms tumor with the ifosfamide, carboplatin, and etoposide regimen. She recovered completely and without sequelae from ifosfamide-induced pancreatitis soon after the drug was stopped. Abdominal pain in patients on anticancer treatment is a common occurrence, but it is rarely investigated. Patients who receive ifosfamide as part of a chemotherapy regimen should be carefully monitored, and symptoms or signs suggestive of acute pancreatitis should be promptly investigated. Withholding the drug usually leads to complete recovery. |
| |
Keywords: | Ifosfamide Acute pancreatitis Recurrent Wilms tumor Cancer chemotherapy Drug toxicity |
本文献已被 ScienceDirect PubMed 等数据库收录! |
|