Effects of inhibitory rTMS on bladder function in Parkinson's disease patients |
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| Authors: | Livia Brusa MD PhD Enrico Finazzi Agrò MD Filomena Petta MD Francesco Sciobica MD Sara Torriero MD Emanuele Lo Gerfo MD Cesare Iani MD Paolo Stanzione MD Giacomo Koch MD |
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| Affiliation: | 1. UOC Neurologia, Ospedale S. Eugenio, Rome;2. Clinica Urologica, Università di Roma Tor Vergata, Rome;3. Fondazione Santa Lucia IRCCS, Rome;4. Clinica Neurologica, Dipartimento di Neuroscienze, Università di Roma Tor Vergata, Rome, Italy |
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| Abstract: | Patients affected by Parkinson's disease (PD) may present with lower urinary tract (LUT) dysfunction characterized by involuntary detrusor overactivity. We evaluated possible impact of a 2‐week course of low frequency 1 Hz repetitive transcranial magnetic stimulation (rTMS) on LUT behavior in eight advanced PD patients complaining of urinary disturbances. We tested the effects of rTMS measuring urodynamic examination and the International Prostate Symptoms Score (IPSS) questionnaire, used for evaluation of subjective LUTS. rTMS was able to improve temporarily LUT behavior in PD patients, increasing bladder capacity and the first sensation of filling phase. Moreover, a reduction of IPSS score was noticed, due to an improvement on filling phase symptoms. The beneficial effects assessed with the IPSS lasted for up to 2 weeks after the end of the stimulation. rTMS seems to be an effective, noninvasive alternative treatment for PD patients with urinary disturbances. © 2009 Movement Disorder Society |
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| Keywords: | bladder functions transcranial magnetic stimulation Parkinson's disease rTMS urodynamic |
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