|
|||||
|
|
Cushing syndrome as a presenting symptom of renal tumors in children |
|
| Authors: | H. Segers MD J.C. van der Heyden MD E.L.T. van den Akker MD PhD R.R. de Krijger MD PhD C.M. Zwaan MD PhD M.M. van den Heuvel‐Eibrink MD PhD |
| Affiliation: | 1. Department of Pediatric Oncology/Hematology, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands;2. Department of Pediatric Endocrinology, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands;3. Department of Pathology, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands |
| Abstract: | Cushing syndrome as the presenting symptom of a malignant renal tumor in children is rare. We report the first case of paraneoplastic Cushing syndrome due to a Wilms tumor, in which clinical and biological signs of hypercortisolism regressed during preoperative chemotherapy. Additionally, we reviewed the literature on paraneoplastic Cushing syndrome secondary to pediatric renal tumors. Pediatr Blood Cancer 2009;53:211–213. © 2009 Wiley‐Liss, Inc. |
| Keywords: | adrenocorticotropic hormone (ACTH) corticotrophin‐releasing hormone (CRH) Cushing syndrome nephroblastoma renal tumor |