Dermatomyositis with inclusion body myositis pathology |
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| Authors: | Robert Layzer MD Han Sung Lee MD PhD Donald Iverson MD Marta Margeta MD PhD |
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| Affiliation: | 1. Department of Neurology, Box 0114, UCSF, University of California, San Francisco, California 94143, USA;2. Department of Pathology, University of California, San Francisco, California, USA;3. Eureka, California, USA |
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| Abstract: | The pathogenic role of inflammation in inclusion body myositis (IBM) remains uncertain. A 63‐year‐old man developed a severe, rapidly progressive myopathy with clinical features typical of dermatomyositis (DM), but muscle pathology was typical of IBM. Treatment with prednisone and methotrexate resulted in complete remission of symptoms. Together with two similar cases reported previously, this case suggests that the inflammatory process of DM may trigger the pathologic changes of IBM. Muscle Nerve, 2009 |
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| Keywords: | dermatomyositis inclusion body myositis muscle pathology corticosteroid therapy methotrexate therapy |
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