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Perineuritis in acute lyme neuroborreliosis |
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| Authors: | Marwa Elamin MRCPI Yazan Alderazi MB Gerard Mullins MRCPI Michael A Farrell FRCPI Sue O'Connell DipClinMicro Timothy J Counihan FRCPI |
| Institution: | 1. Department of Neurology, University College Hospital, Galway, Ireland;2. Department of Neuropathology, Beaumont Hospital, Dublin, Ireland;3. Health Protection Agency Lyme Borreliosis Unit, Southampton General Hospital, Southampton, UK |
| Abstract: | Perineuritis is an unusual cause of direct peripheral nerve injury. We describe the clinicopathologic features of a 56‐year‐old man with mononeuritis multiplex due to Lyme disease; sural nerve biopsy demonstrated florid perineuritis. Treatment with intravenous ceftriaxone resulted in marked neurologic improvement. This study supports the notion that perineuritis forms part of the pathogenesis in acute Lyme neuroborreliosis. Muscle Nerve, 2009 |
| Keywords: | Lyme disease mononeuritis multiplex neuropathy neuroborreliosis perineuritis nerve biopsy |