Spin‐locked balanced steady‐state free‐precession (slSSFP) |
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| Authors: | Walter RT Witschey Ari Borthakur Mark A Elliott Jeremy Magland Erin L McArdle Andrew Wheaton Ravinder Reddy |
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| Institution: | 1. Graduate Group in Biochemistry and Molecular Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania, USA;2. Metabolic Magnetic Resonance Research and Computing Center, Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA;3. Laboratory of Structural NMR Imaging, Department of Radiology, University of Pennsylvania, Pennsylvania, USA |
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| Abstract: | A spin‐locked balanced steady‐state free‐precession (slSSFP) pulse sequence is described that combines a balanced gradient‐echo acquisition with an off‐resonance spin‐lock pulse for fast MRI. The transient and steady‐state magnetization trajectory was solved numerically using the Bloch equations and was shown to be similar to balanced steady‐state free‐precession (bSSFP) for a range of T2/T1 and flip angles, although the slSSFP steady‐state could be maintained with considerably lower radio frequency (RF) power. In both simulations and brain scans performed at 7T, slSSFP was shown to exhibit similar contrast and signal‐to‐noise ratio (SNR) efficiency to bSSFP, but with significantly lower power. Magn Reson Med, 2009. © 2009 Wiley‐Liss, Inc. |
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| Keywords: | spin‐locked SSFP slSSFP trueFISP T1rho |
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